2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-162522
    SL-IN-1
    		Inhibitor
    SL-IN-1 (Compound C6) is an inhibitor for plant hormone steroid lactones receptor (SL receptor). SL-IN-1 promotes rice tillering, inhibits the germination of the root parasite P. aegyptiaca seeds (IC50 is 82.8 µM), delays dark-induced senescence of rice leaves, and protects the leaf membrane from lipid peroxidation.
    SL-IN-1
  • HY-151151
    Trypanothione synthetase-IN-3
    		Inhibitor
    Trypanothione synthetase-IN-3 is a noncompetitive mixed hyperbolic Trypanothione synthetase (TryS) inhibitor (Ki: 0.8 μM). Trypanothione synthetase-IN-3 can be used in the study of parasites, such as L. infantum.
    Trypanothione synthetase-IN-3
  • HY-123718
    6-Benzylthioinosine
    		Inhibitor
    6-Benzylthioinosine is a compound with antileukemic activity that increases cytotoxicity against acute myeloid leukemia cells when combined with metformin, modulating cellular metabolism and signaling pathways through multiple mechanisms.
    6-Benzylthioinosine
  • HY-119893R
    Diamfenetide (Standard)
    		Inhibitor
    Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica.
    Diamfenetide (Standard)
  • HY-155054
    Cysteine protease inhibitor-3
    		Inhibitor
    Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC50s of 0.74 μM, 1.05 μM, 3.5 μM, and 4.9 μM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites.
    Cysteine protease inhibitor-3
  • HY-10572R
    Efavirenz (Standard)
    Efavirenz (Standard) is the analytical standard of Efavirenz. This product is intended for research and analytical applications. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
    Efavirenz (Standard)
  • HY-N6950R
    Hederacolchiside A1 (Standard)
    		Inhibitor
    Hederacolchiside A1 (Standard) is the analytical standard of Hederacolchiside A1. This product is intended for research and analytical applications. Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro.
    Hederacolchiside A1 (Standard)
  • HY-132905
    Antileishmanial agent-2
    		Inhibitor
    Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells.
    Antileishmanial agent-2
  • HY-136200
    Antitrypanosomal agent 2
    		Inhibitor
    Antitrypanosomal agent 2 is a potent and selective trypanosoma brucei inhibitor.
    Antitrypanosomal agent 2
  • HY-180130
    LC-61
    		Inhibitor
    LC-61 is a potent antileishmanial agent with an IC50 of 0.076 µM against intracellular L. infantum.
    LC-61
  • HY-A0059R
    Nifuratel (Standard)
    		Inhibitor
    Nifuratel (Standard) is the analytical standard of Nifuratel. This product is intended for research and analytical applications. Nifuratel (NF 113, SAP 113) is a broad-spectrum antibiotic with activity against bacteria, fungi and trichomonas.
    Nifuratel (Standard)
  • HY-181516
    Anti-Trypanosoma cruzi agent-8
    		Inhibitor
    Anti-Trypanosoma cruzi agent-8 is an anti-Trypanosoma agent and also a Trypanosoma cruzi trypanothione reductase (TcTR) inhibitor, with an IC50 of 3.9 μM against TcTR. Anti-Trypanosoma cruzi agent-8 functionally inhibits the enzymatic activity of TcTR. Anti-Trypanosoma cruzi agent-8 exhibits trypanocidal activity against intracellular Trypanosoma cruzi amastigotes.
    Anti-Trypanosoma cruzi agent-8
  • HY-116045
    PDEB1-IN-1
    		Inhibitor
    PDEB1-IN-1 (Compound 12b) is the derivative of Cilomilast (HY-10790), and serves as an inhibitor for TryPanosoma Brucei PDEB1 (TbrPDEB1) with an IC50 of 0.95 μM. PDEB1-IN-1 inhibits the proliferation of T. Brucei with an EC50 of 26 μM.
    PDEB1-IN-1
  • HY-103583R
    KDU731 (Standard)
    		Inhibitor
    KDU731 (Standard) is the analytical standard of KDU731 (HY-103583). This product is intended for research and analytical applications. KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo. KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety.
    KDU731 (Standard)
  • HY-W778140
    Diethyl phosphate-13C4 sodium
    		Inhibitor
    Diethyl phosphate-13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate-13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos.
    Diethyl phosphate-<sup>13</sup>C<sub>4</sub> sodium
  • HY-P2209
    Nummularine B
    		Inhibitor
    Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis.
    Nummularine B
  • HY-178064
    Antiparasitic agent-29
    		Inhibitor
    Antiparasitic agent-29 (Compound 5) is a Trypanosome alternative oxidase (TAO) inhibitor with an IC50 of 1.3 nM in Trypanosoma brucei. Antiparasitic agent-29 has a broad-spectrum antiparasitic activity against Trypanosoma and Leishmania spp. Antiparasitic agent-29 accumulates in parasite mitochondria, selectively disrupting its energy metabolism and has potent membrane-perturbing activity with no cross-resistance. Antiparasitic agent-29 shows low ecotoxicity in zebrafish and Daphnia magna models. Antiparasitic agent-29 can be used for parasitic diseases like surra and dourine research.
    Antiparasitic agent-29
  • HY-B2028R
    Propargite (Standard)
    		Inhibitor
    Propargite (Standard) is the analytical standard of Propargite. This product is intended for research and analytical applications. Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM. Propargite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargite (Standard)
  • HY-B0937
    Amprolium
    		Inhibitor
    Amprolium is a coccidiostat used in poultry, is a thiamine analogue and blocks the thiamine transporter of Eimeria species by blocking thiamine uptake it prevents carbohydrate synthesis.
    Amprolium
  • HY-N13116
    3-O-(2",3"-Dimethylbutanoyl)-13-O-decanoylingenol
    		Inhibitor
    3-O-(2",3"-Dimethylbutanoyl)-13-O-decanoylingenol (compound 2) is a diterpenoid with antinematode activity, which can be isolated from Euphorbia kansui.
    3-O-(2
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.